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Current Trials

Current Clinical Trials

Medical Research Group of Central Florida

With only a marginal time commitment, you can volunteer to help improve medication and treatments for patients around the world while getting valuable healthcare and medical testing related to the trials at no cost. It’s simple to get started—and there’s no obligation. Simply browse the list of current clinical studies below to see if you qualify.


Info About Migraines and Our Current Migraine Clinical Trial

More than 37 million Americans suffer from 
migraines. However, an untold number of people do not know whether their reoccurring headaches are really a migraine, or not. Less than half of all migraine sufferers have received an actual diagnosis from their healthcare provider. In order to officially declare whether a person is suffering from a migraine or not, the best plan of action is to see a medical professional who can safely assess and diagnosis.

What is a Migraine? 

Medical professionals characterize migraines as a headache of varying intensity, often accompanied by nausea and sensitivity to light and sound. The National Headache Foundation states that migraines are one-sided, pulsating pains of medium to high intensity.

Often, but not always, migraines are preceded or accompanied by Aura, which is usually “visual symptoms such as flashing lights, zigzag lines resembling forts (known as “fortification spectra”), or blind spots in your vision.” Aura can last anywhere from 5 to 20 minutes, or longer.

What Are Differences Between Migraines and Headaches?

What differentiates migraines from headaches is that migraines are defined as “at least 5 headache attacks, lasting 4-72 hours.” The key difference is that a migraine means multiple successive headaches within a short period of time, or prolonged, intense headaches.

Common symptoms of migraines are usually nausea, vomiting, pulsating pain, sensitivity to light and sound, sweating or cold hands.

Our Current Migraine Study

Medical Research Group of Central Florida is currently conducting a study for persons suffering from migraines. Requirements for the study are listed below.

Requirements To Enroll In This Clinical Trial

  • Must be between 18-75 years old
  • Must have a documented history of migraines for the past 12 months or longer

If you feel that you could qualify for this trial, click below and send us your contact info. 

Download File Apply For Trial

Adult BiPolar Must Take Lithium or Depakote

Child Autism

Child Bipolar with Mania

OCD (Obsessive Compulsive Disorder)


What is it?
Depression is one of a range of moods a person feels that can vary from feeling down as a result of having a bad day, to a debilitating feeling of sadness that may overwhelm you and prevent you from performing normal daily tasks. Depression can occur in people of all ages and the episodes can last from a few days to several weeks or months. It is thought that young adults experience depression more frequently, and that it affects twice as many women as men.

What causes it?
The causes of this disorder are not fully understood, but there are many different ideas behind it. There is a belief that depression can be caused by certain stressful situations or major life changes. Even with these stressors, many believe that you must be genetically predisposed to depression. This belief is backed by some evidence of a hereditary link which causes depression. Some depressive disorders can be caused by a simultaneous medical condition. Depression is also linked to substance abuse.

What are the symptoms?
While there are many symptoms, some of the most common are:
• Loss of interest in activities that usually make the individual happy
• Changes in weight
• Changes in sleep patterns (either too much or too little), difficulty falling asleep or waking up earlier than usual
• Feelings of guilt or worthlessness
• Feeling agitated (unable to sit still)
• Frequent episodes of crying
• Feeling of excessive irritability or anxiety
• Difficulty concentrating or making decisions
• Thoughts of death or plans of suicide
How to find out if you are suffering from depression?
Because of the increasing awareness of depression in our society, an accurate assessment for depression is readily available. This can be done by seeking assistance from a psychiatrist, your medical doctor or other mental health professionals. The mental health professional will want to obtain most of the following information to make an accurate diagnosis:
• Complete physical examination, including medical history
• Complete social and psychiatric history
• Survey of current mood and level of functioning
• A mental status examination
• Length of time you are currently experiencing these symptoms
What are the treatment options?
There are many options for the treatment of depression. Currently the most common is the prescribing of medication. Most psychiatrists and physicians combine this medication management with counseling to help to maximize the patient's recovery.
If you are interested in a research study for Depression, contact us to schedule an initial evaluation.
Qualified participants will receive:
• Study related care and medication at no charge
• Compensation for your time and travel
• And…there is no need for health insurance

Download File Apply For Trial

Adult ADHD

Understanding ADD / ADHD in adults

Attention deficit disorder is not just a problem in children. If you were diagnosed with childhood ADD/ADHD, chances are, you’ve carried at least some of the symptoms into adulthood. But even if you were never diagnosed with ADD/ADHD as a child, that doesn’t mean you can’t be affected by it as an adult.

ADD / ADHD: It’s not just for kids

Attention deficit disorder often goes unrecognized throughout childhood. This was especially common in the past, when very few people were aware of ADD/ADHD. Instead of recognizing your symptoms and identifying the real issue, your family, teachers, or other parents may have labeled you a dreamer, a goof-off, a slacker, a troublemaker, or just a bad student.

Alternately, you may have been able to compensate for the symptoms of ADD/ADHD when you were young, only to run into problems as your responsibilities increase. The more balls you’re trying to keep in the air—pursuing a career, raising a family, running a household—the greater the demand on your abilities to organize, focus, and remain calm. This can be challenging for anyone, but if you have ADD/ADHD, it can feel downright impossible.

The good news is that, no matter how it feels, the challenges of attention deficit disorder are beatable. With education, support, and a little creativity, you can learn to manage the symptoms of adult ADD/ADHD—even turning some of your weaknesses into strengths. It’s never too late to turn the difficulties of adult ADD/ADHD around and start succeeding on your own terms.

Download File Apply For Trial


Up to 1% of the population worldwide suffers from Schizophrenia, a disease that first typically manifests itself during adolescence or young adulthood. Symptoms of Schizophrenia are both subtle and dramatic, and tend to fluctuate considerably over time, especially if left untreated.

Symptoms of Schizophrenia are complex since they essentially comprise the entire psychological and cognitive aspects of the brain. The following are some of the core symptoms of Schizophrenia:
• Delusions (believing things that are known not to be true)
• Hallucinations (seeing or hearing things that are not present)
• Disorganized, nonsensical thinking and speaking
• Disorganized behavior
• Diminished capacity to experience emotions
• Social withdraw and isolation

If you have three or more of these symptoms, there is a very good possibility that you may have Schizophrenia. These symptoms may be caused by other neurological disorders, infectious diseases, and extensive drug abuse. Also, prescription and non-prescription medications may cause these symptoms or make them worse.

If you are interested in a research study for Schizophrenia, contact us to schedule an initial evaluation.
Qualified participants will receive:
• Study related care and medication at no charge
• Compensation for your time and travel
• And…there is no need for health insurance

Download File Apply For Trial

ADHD (Attention Deficit Hyperactivity Disorder)

The primary characteristic of attention deficit hyperactivity disorder (ADHD) is a persistent pattern of inattention and/or hyperactivity-impulsivity that interferes with functioning or a child’s development.

The problems occur usually in two or more areas of a person’s life: home, work, school, and social relationships. ADHD is also referred to as attention deficit disorder (ADD) when hyperactivity or impulsivity is not present.

Attention deficit disorder begins in childhood. The symptoms of inattention and hyperactivity need to show themselves in a manner and degree which is inconsistent with the child’s current developmental level. That is, the child’s behavior is significantly more inattentive or hyperactive than that of his or her peers of a similar age.

Several symptoms must be present before age 12 (which is why ADHD is classified as a neurodevelopmental disorder, even if not diagnosed until adulthood). In the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), symptoms were required before age 7. Now the age of 12 is seen as an acceptable criterion because it is often difficult for adults to look retrospectively and establish a precise age of onset for a child. Indeed, adult recall of childhood symptoms tends to be unreliable. Thus, the DSM-5 has added some leeway to the age cut-off.

A person can present with symptoms that are predominantly characterized by inattention, predominantly hyperactivity-impulsivity, or a combination of the two. To meet for each of these ADHD specifiers, a person must exhibit at least 6 symptoms from the appropriate categories below.

Symptoms of Inattention

  • Often fails to give close attention to details or makes careless mistakes in schoolwork, work, or other activities
  • Often has difficulty sustaining attention in tasks or play activities
  • Often does not seem to listen when spoken to directly
  • Often does not follow through on instructions and fails to finish schoolwork, chores, or duties in the workplace (not due to oppositional behavior or failure to understand instructions)
  • Often has difficulty organizing tasks and activities
  • Often avoids, dislikes, or is reluctant to engage in tasks that require sustained mental effort (such as schoolwork or homework)
  • Often loses things necessary for tasks or activities (e.g., toys, school assignments, pencils, books, or tools)
  • Is often easily distracted by extraneous stimuli
  • Is often forgetful in daily activities–even those the person performs regularly (e.g., a routine appointment)

Symptoms of Hyperactivity/Impulsivity

  • Often fidgets with hands or feet or squirms in seat
  • Often leaves seat in classroom or in other situations in which remaining seated is expected
  • Often runs about or climbs excessively in situations in which it is inappropriate (in adolescents or adults, may be limited to subjective feelings of restlessness)
  • Often has difficulty playing or engaging in leisure activities quietly
  • Is often “on the go” or often acts as if “driven by a motor”
  • Often talks excessively


  • Often blurts out answers before questions have been completed
  • Often has difficulty awaiting turn
  • Often interrupts or intrudes on others (e.g., butts into conversations or games)

Symptoms must have persisted for at least 6 months. Some of these symptoms need to have been present as a child, at 12 years old or younger. The symptoms also must exist in at least two separate settings (for example, at school and at home). The symptoms should be creating significant impairment in social, academic or occupational functioning or relationships.

Download File Apply For Trial

Bipolar Disorder - Teens

Info About Bipolar Disorder in Children/Teenagers and Our Current Bipolar Disorder Clinical Trial

Do you notice extreme behavior and/or mood changes in your child? Does your child go from being extremely excited and silly to very sad and/or angry? Do these changes affect how your child acts at school or at home?

Some children and teens with these symptoms may have bipolar disorder, a serious mental illness.

What is Bipolar Disorder? 

Bipolar disorder is a serious brain illness. It is also called manic-depressive illness. Children with bipolar disorder go through unusual mood changes. Sometimes they feel very happy or "up," and are much more active than usual. This is called mania. And sometimes children with bipolar disorder feel very sad and "down," and are much less active than usual. This is called depression.

Bipolar disorder is not the same as the normal ups and downs every kid goes through. The illness can make it hard for a child to do well in school or get along with friends and family members.

With help, they can manage their symptoms and lead successful lives.

How is Bipolar Disorder different in children compared to adults?

When children develop the illness, it is called early-onset bipolar disorder. This type can be more severe than bipolar disorder in older teens and adults. Also, young people with bipolar disorder may have symptoms more often and switch moods more frequently than adults with the illness.

What are the symptoms of Bipolar Disorder? 

Bipolar mood changes are called mood episodes. These mood episodes can either be manic, depressive, or mixed episodes.

Mood episodes are intense. The feelings are strong and happen along with extreme changes in behavior and energy levels.

Children and teens having a manic episode may:

·       Feel very happy or act silly in a way that's unusual

·       Have a very short temper

·       Talk very fast about a lot of different things

·       Have trouble sleeping but not feel tired

·       Have trouble staying focused

·       Exhibit Risky behavior.

Children and teens having a depressive episode may:

·       Feel very sad

·       Complain about pain, such as stomachaches and headaches

·       Sleep too little or too much

·       Feel guilty and worthless

·       Eat too little or too much

·       Have little energy and no interest in fun activities

·       Think about death or suicide.

How is Bipolar Disorder Diagnosed?

An experienced doctor will carefully examine your child. There are no blood tests or brain scans that can diagnose bipolar disorder. Instead, the doctor will ask questions about your child's mood and sleeping patterns. The doctor will also ask about your child's energy and behavior. Sometimes doctors need to know about medical problems in your family, such as depression or alcoholism. The doctor may use tests to see if an illness other than bipolar disorder is causing your child's symptoms.

Our Current Bipolar Disorder Clinical Trial for Children and Teenagers

Medical Research Group of Central Florida is currently conducting a study for children and teenagers who are diagnosed with Bipolar I Disorder.

Requirements To Enroll In This Clinical Trial

·       Must be between 10-17 years old

·       Must be diagnosed with Bipolar I Disorder.*


*If your child is not diagnosed with Bipolar I Disorder but you would still like them to participate in this clinical trial, please contact us regardless.

If you feel that your child could qualify for this trial, click below and send us your contact info. 


Clinical research studies of Bipolar Disorder in children and teenagers are enrolling NOW. If your child qualifies for one of these studies, he or she may receive at NO COST:



·       Fast and frequent access to a local child psychiatrist with no wait.


·       Approved medication for adult and child use at no cost.


·       Payment for the parents' time and travel.


·       All with no insurance required.

If you think your child has Bipolar Disorder, take action now and explore the clinical research option.



Download File Apply For Trial

Schizophrenia - Teens

Does your teenager have schizophrenia? 
If yes, your child may be eligible to participate in an important research study. 

The ILLUMINATE-301 Study is researching an investigational drug for teenagers with active symptoms of schizophrenia. Active symptoms may include believing or experiencing things that are not really true or having disorganized or unusual thoughts. 

Your child may be eligible to participate in the ILLUMINATE-301 Study if they: 
• are 13-17 years of age 
• have been diagnosed with schizophrenia 

To see if your child might qualify for the ILLUMINATE-301 Study, please call 407-330-2262.

Download File Apply For Trial

Child and Teen Depression

Info About Childhood and Teen Depression and Current Clinical Trials

Untreated depression can lead to problems both now and later in life, including poor school performance, reckless behavior, substance abuse, and other social and personal problems.  The good news is that taking action now can reduce these risks, and that you have options.

Common Symptoms of Depression in Children Include:

  • Changes in sleep being either sleeplessness or excessive sleep
  • Frequent feelings of anger or being "on edge"
  • Difficulty with concentrating in school
  • Noticeable changes in desire/ability to function during school, socialize with peers, or participate in extracurricular activities or in the home. 
  • Excessive fatigue and/or low energy
  • Physical complaints that won't respond to treatment
  • Feelings of worthlessness or guilt
  • Impaired thinking or concentration
  • Thoughts of death or suicide

Not all children have all of these symptoms. In fact, most will display different symptoms at different times and in different settings. 

If you think your child may have depression, know that you and your child have options.

Medical Research Group of Central Florida is currently conducting four different clinical trials for children and teenagers who have depression.

 If your child is between the ages of 6 and 17, and has been diagnosed with Major Depression Disorder or simply "Depression", your child can qualify for one of our clinical research studies.

Clinical research studies of child depression are enrolling NOW. If your child qualifies for one of these studies, he or she may receive at NO COST:

  • Fast and frequent access to a local child psychiatrist with no wait.
  • Depression medication approved for use in adults at no cost.
  • Payment for the parents' time and travel.
  • No insurance needed.

If you think your child has depression, take action now and explore the clinical research option.

Download File Apply For Trial

"I have been seeing Dr. Thebaud for a few years now. I even moved to a different county and choose to drive to see him for care each month. I do this because I am comfortable with him treating me and don't think I could find a doctor I like closer to home. My needs were put first."

Patient T

"Dr. T is a really good and caring Doctor. I would recommend him to anyone. Very sensitive and listens really well, and cares about patients problems. The meds have been working like a charm for a year and a half now."

Patient R

"The attention I received while in the clinical study was great. The coordinators were always available to answer my questions and being able to have the one on one attention for my illness allowed me to understand my situation better."

Patient H

SANFORD: 1403 Medical Plaza Drive, Ste 202, Sanford, Florida 32771 | Phone: (407) 330-2262 | Fax: (407) 321-5464

ORANGE CITY: 2725 Rebecca Lane, Ste 107, Orange City, Florida 32763 | Phone: (386) 775-7627 | Fax: (386) 775-0570

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