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Current Trials

Current Clinical Trials

Medical Research Group of Central Florida

With only a marginal time commitment, you can volunteer to help improve medication and treatments for patients around the world while getting valuable healthcare and medical testing related to the trials at no cost. It’s simple to get started—and there’s no obligation. Simply browse the list of current clinical studies below to see if you qualify.

Migraines

Info About Migraines and Our Current Migraine Clinical Trial

More than 37 million Americans suffer from 
migraines. However, an untold number of people do not know whether their reoccurring headaches are really a migraine, or not. Less than half of all migraine sufferers have received an actual diagnosis from their healthcare provider. In order to officially declare whether a person is suffering from a migraine or not, the best plan of action is to see a medical professional who can safely assess and diagnosis.

What is a Migraine? 

Medical professionals characterize migraines as a headache of varying intensity, often accompanied by nausea and sensitivity to light and sound. The National Headache Foundation states that migraines are one-sided, pulsating pains of medium to high intensity.

Often, but not always, migraines are preceded or accompanied by Aura, which is usually “visual symptoms such as flashing lights, zigzag lines resembling forts (known as “fortification spectra”), or blind spots in your vision.” Aura can last anywhere from 5 to 20 minutes, or longer.


What Are Differences Between Migraines and Headaches?

What differentiates migraines from headaches is that migraines are defined as “at least 5 headache attacks, lasting 4-72 hours.” The key difference is that a migraine means multiple successive headaches within a short period of time, or prolonged, intense headaches.

Common symptoms of migraines are usually nausea, vomiting, pulsating pain, sensitivity to light and sound, sweating or cold hands.

Our Current Migraine Study

Medical Research Group of Central Florida is currently conducting a study for persons suffering from migraines. Requirements for the study are listed below.

Requirements To Enroll In This Clinical Trial


  • Must be between 18-75 years old
  • Must have a documented history of migraines for the past 12 months or longer

If you feel that you could qualify for this trial, click below and send us your contact info. 


Download File Apply For Trial

Depression

What is it?
Depression is one of a range of moods a person feels that can vary from feeling down as a result of having a bad day, to a debilitating feeling of sadness that may overwhelm you and prevent you from performing normal daily tasks. Depression can occur in people of all ages and the episodes can last from a few days to several weeks or months. It is thought that young adults experience depression more frequently, and that it affects twice as many women as men.

What causes it?
The causes of this disorder are not fully understood, but there are many different ideas behind it. There is a belief that depression can be caused by certain stressful situations or major life changes. Even with these stressors, many believe that you must be genetically predisposed to depression. This belief is backed by some evidence of a hereditary link which causes depression. Some depressive disorders can be caused by a simultaneous medical condition. Depression is also linked to substance abuse.

What are the symptoms?
While there are many symptoms, some of the most common are:
• Loss of interest in activities that usually make the individual happy
• Changes in weight
• Changes in sleep patterns (either too much or too little), difficulty falling asleep or waking up earlier than usual
• Feelings of guilt or worthlessness
• Feeling agitated (unable to sit still)
• Frequent episodes of crying
• Feeling of excessive irritability or anxiety
• Difficulty concentrating or making decisions
• Thoughts of death or plans of suicide
 
How to find out if you are suffering from depression?
Because of the increasing awareness of depression in our society, an accurate assessment for depression is readily available. This can be done by seeking assistance from a psychiatrist, your medical doctor or other mental health professionals. The mental health professional will want to obtain most of the following information to make an accurate diagnosis:
• Complete physical examination, including medical history
• Complete social and psychiatric history
• Survey of current mood and level of functioning
• A mental status examination
• Length of time you are currently experiencing these symptoms
 
What are the treatment options?
There are many options for the treatment of depression. Currently the most common is the prescribing of medication. Most psychiatrists and physicians combine this medication management with counseling to help to maximize the patient's recovery.
 
If you are interested in a research study for Depression, contact us to schedule an initial evaluation.
Qualified participants will receive:
• Study related care and medication at no charge
• Compensation for your time and travel
• And…there is no need for health insurance

Download File Apply For Trial

Schizophrenia

Up to 1% of the population worldwide suffers from Schizophrenia, a disease that first typically manifests itself during adolescence or young adulthood. Symptoms of Schizophrenia are both subtle and dramatic, and tend to fluctuate considerably over time, especially if left untreated.

Symptoms of Schizophrenia are complex since they essentially comprise the entire psychological and cognitive aspects of the brain. The following are some of the core symptoms of Schizophrenia:
• Delusions (believing things that are known not to be true)
• Hallucinations (seeing or hearing things that are not present)
• Disorganized, nonsensical thinking and speaking
• Disorganized behavior
• Diminished capacity to experience emotions
• Social withdraw and isolation

If you have three or more of these symptoms, there is a very good possibility that you may have Schizophrenia. These symptoms may be caused by other neurological disorders, infectious diseases, and extensive drug abuse. Also, prescription and non-prescription medications may cause these symptoms or make them worse.

If you are interested in a research study for Schizophrenia, contact us to schedule an initial evaluation.
Qualified participants will receive:
• Study related care and medication at no charge
• Compensation for your time and travel
• And…there is no need for health insurance

Download File Apply For Trial

Adult ADHD

Understanding ADD / ADHD in adults

Attention deficit disorder is not just a problem in children. If you were diagnosed with childhood ADD/ADHD, chances are, you’ve carried at least some of the symptoms into adulthood. But even if you were never diagnosed with ADD/ADHD as a child, that doesn’t mean you can’t be affected by it as an adult.

ADD / ADHD: It’s not just for kids

Attention deficit disorder often goes unrecognized throughout childhood. This was especially common in the past, when very few people were aware of ADD/ADHD. Instead of recognizing your symptoms and identifying the real issue, your family, teachers, or other parents may have labeled you a dreamer, a goof-off, a slacker, a troublemaker, or just a bad student.

Alternately, you may have been able to compensate for the symptoms of ADD/ADHD when you were young, only to run into problems as your responsibilities increase. The more balls you’re trying to keep in the air—pursuing a career, raising a family, running a household—the greater the demand on your abilities to organize, focus, and remain calm. This can be challenging for anyone, but if you have ADD/ADHD, it can feel downright impossible.

The good news is that, no matter how it feels, the challenges of attention deficit disorder are beatable. With education, support, and a little creativity, you can learn to manage the symptoms of adult ADD/ADHD—even turning some of your weaknesses into strengths. It’s never too late to turn the difficulties of adult ADD/ADHD around and start succeeding on your own terms.


Download File Apply For Trial

ADHD (Attention Deficit Hyperactivity Disorder)

The primary characteristic of attention deficit hyperactivity disorder (ADHD) is a persistent pattern of inattention and/or hyperactivity-impulsivity that interferes with functioning or a child’s development.

The problems occur usually in two or more areas of a person’s life: home, work, school, and social relationships. ADHD is also referred to as attention deficit disorder (ADD) when hyperactivity or impulsivity is not present.

Attention deficit disorder begins in childhood. The symptoms of inattention and hyperactivity need to show themselves in a manner and degree which is inconsistent with the child’s current developmental level. That is, the child’s behavior is significantly more inattentive or hyperactive than that of his or her peers of a similar age.

Several symptoms must be present before age 12 (which is why ADHD is classified as a neurodevelopmental disorder, even if not diagnosed until adulthood). In the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (DSM-IV), symptoms were required before age 7. Now the age of 12 is seen as an acceptable criterion because it is often difficult for adults to look retrospectively and establish a precise age of onset for a child. Indeed, adult recall of childhood symptoms tends to be unreliable. Thus, the DSM-5 has added some leeway to the age cut-off.

A person can present with symptoms that are predominantly characterized by inattention, predominantly hyperactivity-impulsivity, or a combination of the two. To meet for each of these ADHD specifiers, a person must exhibit at least 6 symptoms from the appropriate categories below.

Symptoms of Inattention

  • Often fails to give close attention to details or makes careless mistakes in schoolwork, work, or other activities
  • Often has difficulty sustaining attention in tasks or play activities
  • Often does not seem to listen when spoken to directly
  • Often does not follow through on instructions and fails to finish schoolwork, chores, or duties in the workplace (not due to oppositional behavior or failure to understand instructions)
  • Often has difficulty organizing tasks and activities
  • Often avoids, dislikes, or is reluctant to engage in tasks that require sustained mental effort (such as schoolwork or homework)
  • Often loses things necessary for tasks or activities (e.g., toys, school assignments, pencils, books, or tools)
  • Is often easily distracted by extraneous stimuli
  • Is often forgetful in daily activities–even those the person performs regularly (e.g., a routine appointment)

Symptoms of Hyperactivity/Impulsivity

Hyperactivity
  • Often fidgets with hands or feet or squirms in seat
  • Often leaves seat in classroom or in other situations in which remaining seated is expected
  • Often runs about or climbs excessively in situations in which it is inappropriate (in adolescents or adults, may be limited to subjective feelings of restlessness)
  • Often has difficulty playing or engaging in leisure activities quietly
  • Is often “on the go” or often acts as if “driven by a motor”
  • Often talks excessively

Impulsivity

  • Often blurts out answers before questions have been completed
  • Often has difficulty awaiting turn
  • Often interrupts or intrudes on others (e.g., butts into conversations or games)

Symptoms must have persisted for at least 6 months. Some of these symptoms need to have been present as a child, at 12 years old or younger. The symptoms also must exist in at least two separate settings (for example, at school and at home). The symptoms should be creating significant impairment in social, academic or occupational functioning or relationships.





Download File Apply For Trial

Bipolar Disorder - Teens

Info About Bipolar Disorder in Children/Teenagers and Our Current Bipolar Disorder Clinical Trial

Do you notice extreme behavior and/or mood changes in your child? Does your child go from being extremely excited and silly to very sad and/or angry? Do these changes affect how your child acts at school or at home?

Some children and teens with these symptoms may have bipolar disorder, a serious mental illness.

What is Bipolar Disorder? 

Bipolar disorder is a serious brain illness. It is also called manic-depressive illness. Children with bipolar disorder go through unusual mood changes. Sometimes they feel very happy or "up," and are much more active than usual. This is called mania. And sometimes children with bipolar disorder feel very sad and "down," and are much less active than usual. This is called depression.

Bipolar disorder is not the same as the normal ups and downs every kid goes through. The illness can make it hard for a child to do well in school or get along with friends and family members.

With help, they can manage their symptoms and lead successful lives.


How is Bipolar Disorder different in children compared to adults?

When children develop the illness, it is called early-onset bipolar disorder. This type can be more severe than bipolar disorder in older teens and adults. Also, young people with bipolar disorder may have symptoms more often and switch moods more frequently than adults with the illness.

What are the symptoms of Bipolar Disorder? 

Bipolar mood changes are called mood episodes. These mood episodes can either be manic, depressive, or mixed episodes.

Mood episodes are intense. The feelings are strong and happen along with extreme changes in behavior and energy levels.

Children and teens having a manic episode may:

·       Feel very happy or act silly in a way that's unusual

·       Have a very short temper

·       Talk very fast about a lot of different things

·       Have trouble sleeping but not feel tired

·       Have trouble staying focused

·       Exhibit Risky behavior.

Children and teens having a depressive episode may:

·       Feel very sad

·       Complain about pain, such as stomachaches and headaches

·       Sleep too little or too much

·       Feel guilty and worthless

·       Eat too little or too much

·       Have little energy and no interest in fun activities

·       Think about death or suicide.


How is Bipolar Disorder Diagnosed?

An experienced doctor will carefully examine your child. There are no blood tests or brain scans that can diagnose bipolar disorder. Instead, the doctor will ask questions about your child's mood and sleeping patterns. The doctor will also ask about your child's energy and behavior. Sometimes doctors need to know about medical problems in your family, such as depression or alcoholism. The doctor may use tests to see if an illness other than bipolar disorder is causing your child's symptoms.

Our Current Bipolar Disorder Clinical Trial for Children and Teenagers

Medical Research Group of Central Florida is currently conducting a study for children and teenagers who are diagnosed with Bipolar I Disorder.

Requirements To Enroll In This Clinical Trial

·       Must be between 10-17 years old

·       Must be diagnosed with Bipolar I Disorder.*

 

*If your child is not diagnosed with Bipolar I Disorder but you would still like them to participate in this clinical trial, please contact us regardless.


If you feel that your child could qualify for this trial, click below and send us your contact info. 

 

Clinical research studies of Bipolar Disorder in children and teenagers are enrolling NOW. If your child qualifies for one of these studies, he or she may receive at NO COST:

 


     

·       Fast and frequent access to a local child psychiatrist with no wait.

 

·       Approved medication for adult and child use at no cost.

 

·       Payment for the parents' time and travel.

 

·       All with no insurance required.




If you think your child has Bipolar Disorder, take action now and explore the clinical research option.

 

 


Download File Apply For Trial

Alzheimer's Disease

Alzheimer’s disease is a progressive memory loss that first impacts your ability to remember recent events and then, as the disease progresses, impacts events of the past, including even remembering who people are. Although Alzheimer’s disease can occur in people in their 40s and 50s, it is typically a disease seen later in life as people reach their 60s and 70s.

Some of the core symptoms of Alzheimer’s disease, which typically affect people gradually over years, include the following:

• Forgetfulness or trouble remembering recent events
• Difficulty learning new information
• Difficulty putting your thoughts into words
• Trouble organizing information in your mind
• Periods of irritability and impatience
• Difficulty identifying what objects are and how they are used
• Difficulty remembering who people are

If you have three or more of the symptoms, there is a possibility that you may have Alzheimer’s disease. Alzheimer’s disease may mimic other conditions including other types of dementia (conditions that cause memory loss), other neurological disorders, depression, alcohol and drug abuse, metabolic disorders, and even ADD/ADHD and severe stress. Also, numerous prescription and non-prescription medications may also cause these symptoms or make them worse.

If you are interested in a research study for Alzheimer’s, contact us to schedule an initial evaluation. 

Qualified participants will receive: 
 • Study related care and medication at no charge
 • Compensation for your time and travel
 • And…there is no need for health insurance

Download File Apply For Trial

Schizophrenia - Teens

Does your teenager have schizophrenia? 
If yes, your child may be eligible to participate in an important research study. 

The ILLUMINATE-301 Study is researching an investigational drug for teenagers with active symptoms of schizophrenia. Active symptoms may include believing or experiencing things that are not really true or having disorganized or unusual thoughts. 

Your child may be eligible to participate in the ILLUMINATE-301 Study if they: 
• are 13-17 years of age 
• have been diagnosed with schizophrenia 

To see if your child might qualify for the ILLUMINATE-301 Study, please call 407-330-2262.

Download File Apply For Trial

Child and Teen Depression

Info About Childhood and Teen Depression and Current Clinical Trials

Untreated depression can lead to problems both now and later in life, including poor school performance, reckless behavior, substance abuse, and other social and personal problems.  The good news is that taking action now can reduce these risks, and that you have options.

Common Symptoms of Depression in Children Include:

  • Changes in sleep being either sleeplessness or excessive sleep
  • Frequent feelings of anger or being "on edge"
  • Difficulty with concentrating in school
  • Noticeable changes in desire/ability to function during school, socialize with peers, or participate in extracurricular activities or in the home. 
  • Excessive fatigue and/or low energy
  • Physical complaints that won't respond to treatment
  • Feelings of worthlessness or guilt
  • Impaired thinking or concentration
  • Thoughts of death or suicide

Not all children have all of these symptoms. In fact, most will display different symptoms at different times and in different settings. 

If you think your child may have depression, know that you and your child have options.

Medical Research Group of Central Florida is currently conducting four different clinical trials for children and teenagers who have depression.

 If your child is between the ages of 6 and 17, and has been diagnosed with Major Depression Disorder or simply "Depression", your child can qualify for one of our clinical research studies.

Clinical research studies of child depression are enrolling NOW. If your child qualifies for one of these studies, he or she may receive at NO COST:



  • Fast and frequent access to a local child psychiatrist with no wait.
  • Depression medication approved for use in adults at no cost.
  • Payment for the parents' time and travel.
  • No insurance needed.

If you think your child has depression, take action now and explore the clinical research option.

Download File Apply For Trial

Smoking Cessation - Teens

Long-term tobacco smoking can have adverse effects in nearly every organ of the body and cause a variety of diseases. In the United States, the adverse health effects from cigarette smoking account for more than 400,000 deaths among adults, or nearly one of every five deaths; more deaths are caused each year by tobacco use than by all deaths from human immunodeficiency virus (HIV), illegal drug use, alcohol use, motor vehicle injuries, suicides, and murders combined.

Do you want to stop smoking but need the extra support to do so? If so and you are between the ages of 12-16, you may be able to take part of a Clinical Research Study for teens that smoke.


To qualify you must be a current smoker between the ages of 12-16 and willing make an attempt to quit. 

Study Benefits Include at no cost to you:

  • One on One time with a Physician and study-related medical assessments
  • Study-related medication, currently on the market for Adults
  • Compensation for your time and travel

To learn more please complete our online form and one of our study coordinators will be in touch with you.


Download File Apply For Trial

Fibromyalgia


Fibromyalgia is the most common musculoskeletal condition after osteoarthritis. Still, it is often misdiagnosed and misunderstood. Its characteristics include widespread muscle and joint pain and fatigue, as well as other symptoms. Fibromyalgia can lead to depression and social isolation.

This overview of fibromyalgia syndrome (FMS) covers symptoms, diagnosis, and both standard and alternative treatments.

What Is Fibromyalgia Syndrome?

A syndrome is a set of symptoms. When they exist together, they imply the presence of a specific disease or a greater chance of developing the disease. With fibromyalgia syndrome, the following symptoms commonly occur together:

  • Anxiety or depression
  • Decreased pain threshold or tender points
  • Incapacitating fatigue
  • Widespread pain

 

Are Women More Likely to Get Fibromyalgia Than Men?

More than 12 million Americans have fibromyalgia. Most of them are women ranging in age from 25 to 60. Women are 10 times more likely to get this disease than men.

What Are Fibromyalgia Symptoms?

Fibromyalgia causes you to ache all over. You may have symptoms of crippling fatigue -- even on arising. Specific tender points on the body may be painful to touch. You may experience swelling, disturbances in deep-level or restful sleep, and mood disturbances or depression.

Your muscles may feel like they have been overworked or pulled. They'll feel that way even without exercise or another cause. Sometimes, your muscles twitch, burn, or have deep stabbing pain.

Some patients with fibromyalgia have pain and achiness around the joints in the neck, shoulder, back, and hips. This makes it difficult for them to sleep or exercise. Other fibromyalgia symptoms include:

  • Abdominal pain
  • Chronic headaches
  • Dryness in mouth, nose, and eyes
  • Hypersensitivity to cold and/or heat
  • Inability to concentrate (called "fibro fog")
  • Incontinence
  • Irritable bowel syndrome
  • Numbness or tingling in the fingers and feet
  • Stiffness

Fibromyalgia can cause signs and feelings similar to osteoarthritis, bursitis, andtendinitis. Some experts include it in this group of arthritis and related disorders. However, while the pain of bursitis or tendinitis is localized to a specific area, pain and stiffness with fibromyalgia are widespread.

If you are interested in a research study for Fibromyalgia, contact us to schedule an initial evaluation. Qualified participants will receive:
• Study related care and medication at no charge
• Compensation for your time and travel
• And…there is no need for health insurance

Download File Apply For Trial

Generalized Anxiety Disorder (GAD)

Generalized Anxiety Disorder (GAD) occurs in approximately 5% of Americans and impacts every area of life. It is a condition that is considerably more than just being nervous, cautious or appropriately “worried” about specific events. The symptoms of GAD tend to come and go over time, but rarely ever completely subside.

Some of the core symptoms of GAD include the following:
• Chronic, continual worry
• Feeling restless or hyper
• Inability to relax
• Fatigue
• Unable to concentrate
• Irritability
• Muscle tension, including headaches
• Disrupted sleep
• Gastrointestinal symptoms such as indigestion, nausea or diarrhea

If you have three or more of these symptoms, there is a very good possibility that you may have GAD. These symptoms may be caused by, or occur with, other medical conditions including depression, bipolar disorders, thyroid disease and other endocrinological disorders. Also, prescription and non-prescription medications and supplements may cause these symptoms or make them worse.

If you are interested in a research study for Generalized Anxiety Disorder, contact us to schedule an initial evaluation.
Qualified participants will receive:
• Study related care and medication at no charge
• Compensation for your time and travel
• And…there is no need for health insurance

Download File Apply For Trial

"Dr. T is a really good and caring Doctor. I would recommend him to anyone. Very sensitive and listens really well, and cares about patients problems. The meds have been working like a charm for a year and a half now."

Patient R

"The attention I received while in the clinical study was great. The coordinators were always available to answer my questions and being able to have the one on one attention for my illness allowed me to understand my situation better."

Patient H

"I have been seeing Dr. Thebaud for a few years now. I even moved to a different county and choose to drive to see him for care each month. I do this because I am comfortable with him treating me and don't think I could find a doctor I like closer to home. My needs were put first."

Patient T

SANFORD: 1403 Medical Plaza Drive, Ste 202, Sanford, Florida 32771 | Phone: (407) 330-2262 | Fax: (407) 321-5464

ORANGE CITY: 2725 Rebecca Lane, Ste 107, Orange City, Florida 32763 | Phone: (386) 775-7627 | Fax: (386) 775-0570

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